maladaptive responses to immune disorders.

Discussion on Maladaptive Immune Disorders

HIV and Psoriasis are the selected immune diseases.

HIV is a viral infection that attacks the body’s immune system, specifically CD4 cells, and impairs their ability to fight infections. It is the virus that enters CD4 cells and replicates before destroying them. This results in a compromised immune system. HIV triggers the immune system to activate, resulting chronic inflammation and immune activation. This can eventually lead to AIDS. HIV can cause maladaptive reactions, including opportunistic infection and certain cancers such as Kaposi’s sarcoma.

The skin is affected by a chronic, autoimmune disease that causes red, scaly spots. Psoriasis is caused by a proliferation of keratinocytes, which results in plaque formation. Psoriasis triggers an immune reaction that involves activating T cells, and other immune cell types in the skin. This results in inflammation. Psoriasis can cause joint inflammation or psoriatic arthritis, as well as an increase in cardiovascular risk.

Behavior is the factor chosen. Smoking, alcohol abuse, and a poor diet are all behaviors that can have a negative impact on the pathophysiology for HIV as well as psoriasis. Smoking and alcohol can cause chronic inflammation and immune activation, and this can weaken your immune system. A poor diet can weaken your immune system and make you more vulnerable to infection. Smoking has also been proven to worsen psoriasis and make it harder to control. Alcohol and poor nutrition can worsen the condition as they increase inflammation.