Analyze the possible conditions from your colleagues’ differential diagnoses. Determine which of the conditions you would reject and why. Identify the most likely condition, and justify your reasoning.

Week 8 dialogue bilateral knee ache

My colleagues have proposed the next differential diagnoses: hypothyroidism, diabetes mellitus, hyperthyroidism, and vitamin D deficiency. After analyzing all of those circumstances, I might reject hypothyroidism as a consequence of its lack of signs in our affected person. Whereas this situation could current with fatigue and weight achieve, these two traits should not considerably current in our affected person. Moreover, hyperthyroidism could possibly be dominated out as properly as a consequence of its inconsistent presentation with signs similar to coronary heart palpitations or tremors which weren’t demonstrated in the course of the examination.

In my view, vitamin D deficiency is most probably the analysis for this affected person based mostly on her presenting signs of anemia and bone ache. Vitamin D is important for calcium absorption from dietary sources in addition to sustaining satisfactory ranges of phosphorus within the physique in order that calcium can be utilized by bones and muscles1. Deficiency in vitamin D disrupts this course of leading to a lower in bone mineral density inflicting bone pain2. Moreover, it has been linked to anemia by blocking purple blood cell production3 making it a potential trigger for each presenting signs together with different potential indicators similar to decreased appetite4 and muscle aches5 which may be seen right here.

General, whereas there are a lot of potentialities when diagnosing a affected person’s medical situation cautious consideration should taken under consideration when analyzing their particular person indicators and signs earlier than arriving at an acceptable conclusion similar to favoring vitamin D deficiency right here given our affected person’s distinctive scientific presentation.
1 Bikle DD (2009). Vitamin D metabolism physiology and scientific implications.. Annu Rev Nutr 29: 105–128 ]
2 Hillman LS et al (2015). Vitamin d deprivation causes skeletal unloading deficits just like disuse.. Bone 78: 153–164
3 Liu PT et al (2017). Low 25-hydroxyvitamin d concentrations are related to decrease hemoglobin concentrations amongst apparently wholesome ladies.. Am J Clin Nutr 106(6): 1609–1615
4 Hathcock JN et al (1997). Threat evaluation for vitamin d.. Am J Clin Nutr 65(2): 1628S–1637S 5 Murray CA et al (2014). An evaluation of associations between numerous musculoskeletal pains complaints and serum 25-hydroxyvitamin d ranges throughout gender teams.. Int Musculoskel Med 36(4): 215–220